CaBagE: A Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing

A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype structures, or tandem repeats. Long-read sequencing technologies, such as Oxford Nanopore’s MinION, enable direct measurement of complex loci without...

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Detalles Bibliográficos
Autores principales: Wallace, Amelia D., Sasani, Thomas A., Swanier, Jordan, Gates, Brooke L., Greenland, Jeff, Pedersen, Brent S., Varley, Katherine E., Quinlan, Aaron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031414/
https://www.ncbi.nlm.nih.gov/pubmed/33830997
http://dx.doi.org/10.1371/journal.pone.0241253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031414/
https://www.ncbi.nlm.nih.gov/pubmed/33830997
http://dx.doi.org/10.1371/journal.pone.0241253

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