Cargando…
CaBagE: A Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing
A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype structures, or tandem repeats. Long-read sequencing technologies, such as Oxford Nanopore’s MinION, enable direct measurement of complex loci without...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031414/ https://www.ncbi.nlm.nih.gov/pubmed/33830997 http://dx.doi.org/10.1371/journal.pone.0241253 |