A human coronavirus evolves antigenically to escape antibody immunity

There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronavirus 229E. We identify human sera from the 1980s a...

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Detalles Bibliográficos
Autores principales: Eguia, Rachel T., Crawford, Katharine H. D., Stevens-Ayers, Terry, Kelnhofer-Millevolte, Laurel, Greninger, Alexander L., Englund, Janet A., Boeckh, Michael J., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031418/
https://www.ncbi.nlm.nih.gov/pubmed/33831132
http://dx.doi.org/10.1371/journal.ppat.1009453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031418/
https://www.ncbi.nlm.nih.gov/pubmed/33831132
http://dx.doi.org/10.1371/journal.ppat.1009453

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