Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer

BACKGROUND: Caveolae proteins play diverse roles in cancer development and progression. In prostate cancer, non‐caveolar caveolin‐1 (CAV1) promotes metastasis, while CAVIN1 attenuates CAV1‐induced metastasis. Here, we unveil a novel mechanism linking CAV1 to selective loading of exosomes with metast...

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Detalles Bibliográficos
Autores principales: Robinson, Harley, Ruelcke, Jayde E., Lewis, Amanda, Bond, Charles S., Fox, Archa H., Bharti, Vandhana, Wani, Shivangi, Cloonan, Nicole, Lai, Andrew, Margolin, David, Li, Li, Salomon, Carlos, Richards, Renée S., Farrell, Aine, Gardiner, Robert A., Parton, Robert G., Cristino, Alexandre S., Hill, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031663/
https://www.ncbi.nlm.nih.gov/pubmed/33931969
http://dx.doi.org/10.1002/ctm2.381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031663/
https://www.ncbi.nlm.nih.gov/pubmed/33931969
http://dx.doi.org/10.1002/ctm2.381

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