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Using the antibody-antigen binding interface to train image-based deep neural networks for antibody-epitope classification

High-throughput B-cell sequencing has opened up new avenues for investigating complex mechanisms underlying our adaptive immune response. These technological advances drive data generation and the need to mine and analyze the information contained in these large datasets, in particular the identific...

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Detalles Bibliográficos
Autores principales: Ripoll, Daniel R., Chaudhury, Sidhartha, Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032195/
https://www.ncbi.nlm.nih.gov/pubmed/33780441
http://dx.doi.org/10.1371/journal.pcbi.1008864