Cargando…
Aberrant TGF-β1 signaling activation by MAF underlies pathological lens growth in high myopia
High myopia is a leading cause of blindness worldwide. Myopia progression may lead to pathological changes of lens and affect the outcome of lens surgery, but the underlying mechanism remains unclear. Here, we find an increased lens size in highly myopic eyes associated with up-regulation of β/γ-cry...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032689/ https://www.ncbi.nlm.nih.gov/pubmed/33833231 http://dx.doi.org/10.1038/s41467-021-22041-2 |