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Aberrant TGF-β1 signaling activation by MAF underlies pathological lens growth in high myopia

High myopia is a leading cause of blindness worldwide. Myopia progression may lead to pathological changes of lens and affect the outcome of lens surgery, but the underlying mechanism remains unclear. Here, we find an increased lens size in highly myopic eyes associated with up-regulation of β/γ-cry...

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Detalles Bibliográficos
Autores principales:	Zhu, Xiangjia, Du, Yu, Li, Dan, Xu, Jie, Wu, Qingfeng, He, Wenwen, Zhang, Keke, Zhu, Jie, Guo, Linying, Qi, Ming, Liu, Ailin, Qi, Jiao, Wang, Guangyu, Meng, Jiaqi, Yang, Zhenglin, Zhang, Kang, Lu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032689/ https://www.ncbi.nlm.nih.gov/pubmed/33833231 http://dx.doi.org/10.1038/s41467-021-22041-2

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