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Modular synthesis of chiral 1,2-dihydropyridines via Mannich/Wittig/cycloisomerization sequence that internally reuses waste

1,2-Dihydropyridines are valuable and reactive synthons, and particularly useful precursors to synthesize piperidines and pyridines that are among the most common structural components of pharmaceuticals. However, the catalytic enantioselective synthesis of structurally diverse 1,2-dihydropyridines...

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Detalles Bibliográficos
Autores principales: Mu, Bo-Shuai, Cui, Xiao-Yuan, Zeng, Xing-Ping, Yu, Jin-Sheng, Zhou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032725/
https://www.ncbi.nlm.nih.gov/pubmed/33833227
http://dx.doi.org/10.1038/s41467-021-22374-y