Actin cytoskeletal inhibitor 19,20-epoxycytochalasin Q sensitizes yeast cells lacking ERG6 through actin-targeting and secondarily through disruption of lipid homeostasis

Repetitive uses of antifungals result in a worldwide crisis of drug resistance; therefore, natural fungicides with minimal side-effects are currently sought after. This study aimed to investigate antifungal property of 19, 20-epoxycytochalasin Q (ECQ), derived from medicinal mushroom Xylaria sp. BCC...

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Detalles Bibliográficos
Autores principales: Watchaputi, Kwanrutai, Somboon, Pichayada, Phromma-in, Nipatthra, Ratanakhanokchai, Khanok, Soontorngun, Nitnipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032726/
https://www.ncbi.nlm.nih.gov/pubmed/33833332
http://dx.doi.org/10.1038/s41598-021-87342-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032726/
https://www.ncbi.nlm.nih.gov/pubmed/33833332
http://dx.doi.org/10.1038/s41598-021-87342-4

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