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A deep learning approach to identifying immunogold particles in electron microscopy images

Electron microscopy (EM) enables high-resolution visualization of protein distributions in biological tissues. For detection, gold nanoparticles are typically used as an electron-dense marker for immunohistochemically labeled proteins. Manual annotation of gold particle labels is laborious and time...

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Detalles Bibliográficos
Autores principales: Jerez, Diego, Stuart, Eleanor, Schmitt, Kylie, Guerrero-Given, Debbie, Christie, Jason M., Hahn, William E., Kamasawa, Naomi, Smirnov, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032809/
https://www.ncbi.nlm.nih.gov/pubmed/33833289
http://dx.doi.org/10.1038/s41598-021-87015-2