Conversion of Reactive Astrocytes to Induced Neurons Enhances Neuronal Repair and Functional Recovery After Ischemic Stroke

The master neuronal transcription factor NeuroD1 can directly reprogram astrocytes into induced neurons (iNeurons) after stroke. Using viral vectors to drive ectopic ND1 expression in gliotic astrocytes after brain injury presents an autologous form of cell therapy for neurodegenerative disease. Cul...

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Detalles Bibliográficos
Autores principales: Jiang, Michael Qize, Yu, Shan Ping, Wei, Zheng Zachory, Zhong, Weiwei, Cao, Wenyuan, Gu, Xiaohuan, Wu, Anika, McCrary, Myles Randolph, Berglund, Ken, Wei, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032905/
https://www.ncbi.nlm.nih.gov/pubmed/33841125
http://dx.doi.org/10.3389/fnagi.2021.612856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032905/
https://www.ncbi.nlm.nih.gov/pubmed/33841125
http://dx.doi.org/10.3389/fnagi.2021.612856

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