VEGFR Inhibitors for Uterine Metastatic Perivascular Epithelioid Tumors (PEComa) Resistant to mTOR Inhibitors. A Case Report and Review of Literature

Uterine perivascular epithelioid cell tumors (PEComas) are rare neoplasms. PI3K/AKT/mTOR pathway upregulation is critical for their pathogenesis and is often associated with TSC1/TSC2 inactivation. Although first line mTOR inhibitors are an effective treatment, metastatic PEComas eventually progress...

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Detalles Bibliográficos
Autores principales: Liapi, Aikaterini, Mathevet, Patrice, Herrera, Fernanda G., Hastir, Delfyne, Sarivalasis, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032946/
https://www.ncbi.nlm.nih.gov/pubmed/33842348
http://dx.doi.org/10.3389/fonc.2021.641376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032946/
https://www.ncbi.nlm.nih.gov/pubmed/33842348
http://dx.doi.org/10.3389/fonc.2021.641376

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