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The Spectrum, Tendency and Predictive Value of PIK3CA Mutation in Chinese Colorectal Cancer Patients

BACKGROUND: PIK3CA is a high-frequency mutation gene in colorectal cancer, while its prognostic value remains unclear. This study evaluated the mutation tendency, spectrum, prognosis power and predictive power in cetuximab treatment of PIK3CA in Chinese CRC cohort. METHODS: The PIK3CA exon 9 and 20...

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Detalles Bibliográficos
Autores principales: Fu, Xinhui, Lin, Hanjie, Fan, Xinjuan, Zhu, Yaxi, Wang, Chao, Chen, Zhiting, Tan, Xiaoli, Huang, Jinglin, Cai, Yacheng, Huang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032977/
https://www.ncbi.nlm.nih.gov/pubmed/33842311
http://dx.doi.org/10.3389/fonc.2021.595675