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Prognostic Impact of PCK1 Protein Kinase Activity-Dependent Nuclear SREBP1 Activation in Non-Small-Cell Lung Carcinoma

Metabolic enzymes can perform non-metabolic functions and play critical roles in the regulation of a variety of important cellular activities. Phosphoenolpyruvate carboxykinase 1 (PCK1), a gluconeogenesis enzyme, was recently identified as an AKT-regulated protein kinase that phosphorylates INSIG1/2...

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Detalles Bibliográficos
Autores principales: Shao, Fei, Bian, Xueli, Wang, Juhong, Xu, Daqian, Guo, Wei, Jiang, Hongfei, Zhao, Gaoxiang, Zhu, Lei, Wang, Shuai, Xing, Dongming, Gao, Yibo, He, Jie, Lu, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033018/
https://www.ncbi.nlm.nih.gov/pubmed/33842305
http://dx.doi.org/10.3389/fonc.2021.561247