The Enigma of Substrate Recognition and Catalytic Efficiency of APE1-Like Enzymes

Despite significant achievements in the elucidation of the nature of protein-DNA contacts that control the specificity of nucleotide incision repair (NIR) by apurinic/apyrimidinic (AP) endonucleases, the question on how a given nucleotide is accommodated by the active site of the enzyme remains unan...

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Detalles Bibliográficos
Autores principales: Davletgildeeva, Anastasiia T., Ishchenko, Alexander A., Saparbaev, Murat, Fedorova, Olga S., Kuznetsov, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033172/
https://www.ncbi.nlm.nih.gov/pubmed/33842455
http://dx.doi.org/10.3389/fcell.2021.617161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033172/
https://www.ncbi.nlm.nih.gov/pubmed/33842455
http://dx.doi.org/10.3389/fcell.2021.617161

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