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Rosavin suppresses osteoclastogenesis in vivo and in vitro by blocking the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways

BACKGROUND: Bone homeostasis is mediated by osteoblast-related bone formation and osteoclast-related resorption. The imbalance of bone homeostasis due to excessive osteoclastogenesis or reduced osteogenesis can result in various disorders, such as postmenopausal osteoporosis (PMOP). The receptor act...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhao, Zhang, Weijie, Huo, Liang, Chai, Ying, Liu, Zhiyang, Ren, Zhenhu, Yu, Chuangqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033352/
https://www.ncbi.nlm.nih.gov/pubmed/33842604
http://dx.doi.org/10.21037/atm-20-4255