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Homologous recombination repair gene mutations show no survival benefits in Chinese high-grade serous ovarian cancer patients

BACKGROUND: The purpose of our study was to identify germline and somatic homologous recombination repair (HRR) pathway gene mutations and their clinical-prognostic impact in Chinese high-grade serous ovarian cancer (HGSC) patients. METHODS: We applied next-generation sequencing (NGS) in consecutive...

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Detalles Bibliográficos
Autores principales: Feng, Zheng, Wen, Hao, Ju, Xingzhu, Bi, Rui, Chen, Xiaojun, Yang, Wentao, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033363/
https://www.ncbi.nlm.nih.gov/pubmed/33842585
http://dx.doi.org/10.21037/atm-20-5136