AB013. CXCL4-DNA immune complexes drive inflammation in systemic sclerosis by amplifying TLR9-mediated interferon-α production

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation-driven tissue fibrosis and vasculopathy. CXCL4 is a chemokine overexpressed in SSc and represents an early serum biomarker of severe disease. CXCL4 likely contributes to inflammation via chemokine signaling pathwa...

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Detalles Bibliográficos
Autores principales: Lee, Ernest Y., Lande, Roberto, Chizzolini, Carlo, Wong, Gerard C. L., Frasca, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Abstract on Rheumatologic Skin Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033366/
http://dx.doi.org/10.21037/atm.2021.AB013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033366/
http://dx.doi.org/10.21037/atm.2021.AB013

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