Inhibitory Smads suppress pancreatic stellate cell activation through negative feedback in chronic pancreatitis

BACKGROUND: Activation of pancreatic stellate cells (PSCs) is a key cause of chronic pancreatitis (CP), while inhibition of transforming growth factor-β (TGF-β) signaling renders PSCs inactive. Inhibitory Smads (I-Smads) impede TGF-β intracellular signaling and may provide a way to alleviate CP. Thu...

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Detalles Bibliográficos
Autores principales: Lin, Hao, Dong, Beibei, Qi, Liang, Wei, Yingxiang, Zhang, Yusha, Cai, Xiaotian, Zhang, Qi, Li, Jia, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033383/
https://www.ncbi.nlm.nih.gov/pubmed/33842605
http://dx.doi.org/10.21037/atm-20-4282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033383/
https://www.ncbi.nlm.nih.gov/pubmed/33842605
http://dx.doi.org/10.21037/atm-20-4282

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