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Wnt signaling inhibition confers induced synthetic lethality to PARP inhibitors

Despite considerable efforts, therapeutic strategies targeting the Wnt pathway are still not clinically available. The pervasive role of Wnt‐βcatenin signaling for the control of stem cells during normal tissue homeostasis makes the on‐target toxicity of available therapeutic grade molecules an impo...

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Detalles Bibliográficos
Autor principal:	Angers, Stephane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	News & Views
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033510/ https://www.ncbi.nlm.nih.gov/pubmed/33787008 http://dx.doi.org/10.15252/emmm.202114002

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