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Low immunogenicity of malaria pre‐erythrocytic stages can be overcome by vaccination

Immunogenicity is considered one important criterion for progression of candidate vaccines to further clinical evaluation. We tested this assumption in an infection and vaccination model for malaria pre‐erythrocytic stages. We engineered Plasmodium berghei parasites that harbour a well‐characterised...

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Detalles Bibliográficos
Autores principales: Müller, Katja, Gibbins, Matthew P, Roberts, Mark, Reyes‐Sandoval, Arturo, Hill, Adrian V S, Draper, Simon J, Matuschewski, Kai, Silvie, Olivier, Hafalla, Julius Clemence R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033512/
https://www.ncbi.nlm.nih.gov/pubmed/33709544
http://dx.doi.org/10.15252/emmm.202013390