Synonymous mutations that regulate translation speed might play a non-negligible role in liver cancer development

BACKGROUND: Synonymous mutations do not change the protein sequences. Automatically, they have been regarded as neutral events and are ignored in the mutation-based cancer studies. However, synonymous mutations will change the codon optimality, resulting in altered translational velocity. METHODS: W...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qun, Li, Jian, Yu, Chun-peng, Chang, Shuai, Xie, Ling-ling, Wang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033552/
https://www.ncbi.nlm.nih.gov/pubmed/33836673
http://dx.doi.org/10.1186/s12885-021-08131-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033552/
https://www.ncbi.nlm.nih.gov/pubmed/33836673
http://dx.doi.org/10.1186/s12885-021-08131-w

Ejemplares similares