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Synonymous mutations that regulate translation speed might play a non-negligible role in liver cancer development
BACKGROUND: Synonymous mutations do not change the protein sequences. Automatically, they have been regarded as neutral events and are ignored in the mutation-based cancer studies. However, synonymous mutations will change the codon optimality, resulting in altered translational velocity. METHODS: W...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033552/ https://www.ncbi.nlm.nih.gov/pubmed/33836673 http://dx.doi.org/10.1186/s12885-021-08131-w |