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Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple Sclerosis

[Image: see text] The modulation of the endocannabinoid system (ECS) has shown positive results in animal models of multiple sclerosis (MS) and immune and inflammatory disorders. However, chronic administration of CB1 receptor agonists and degrading enzyme inhibitors can lead to CB1 receptor desensi...

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Detalles Bibliográficos
Autores principales: Reynoso-Moreno, Ines, Tietz, Silvia, Vallini, Erika, Engelhardt, Britta, Gertsch, Jürg, Chicca, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033750/
https://www.ncbi.nlm.nih.gov/pubmed/33860200
http://dx.doi.org/10.1021/acsptsci.0c00214