Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry

[Image: see text] The development of highly selective and fast biocompatible reactions for ligation and cleavage has paved the way for new diagnostic and therapeutic applications of pretargeted in vivo chemistry. The concept of bioorthogonal pretargeting has attracted considerable interest, in parti...

Descripción completa

Detalles Bibliográficos
Autores principales: Stéen, E. Johanna L., Jørgensen, Jesper T., Denk, Christoph, Battisti, Umberto M., Nørregaard, Kamilla, Edem, Patricia E., Bratteby, Klas, Shalgunov, Vladimir, Wilkovitsch, Martin, Svatunek, Dennis, Poulie, Christian B. M., Hvass, Lars, Simón, Marina, Wanek, Thomas, Rossin, Raffaella, Robillard, Marc, Kristensen, Jesper L., Mikula, Hannes, Kjaer, Andreas, Herth, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033778/
https://www.ncbi.nlm.nih.gov/pubmed/33860205
http://dx.doi.org/10.1021/acsptsci.1c00007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033778/
https://www.ncbi.nlm.nih.gov/pubmed/33860205
http://dx.doi.org/10.1021/acsptsci.1c00007

Ejemplares similares