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N/OFQ modulates orofacial pain induced by tooth movement through CGRP-dependent pathways

BACKGROUND: Nociceptin/orphanin FQ (N/OFQ) has been revealed to play bidirectional roles in orofacial pain modulation. Calcitonin gene-related peptide (CGRP) is a well-known pro-nociceptive molecule that participates in the modulation of orofacial pain. We aimed to determine the effects of N/OFQ on...

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Detalles Bibliográficos
Autores principales: Yan, Xinyu, Han, Han, Zhang, Shizhen, Lu, Yanzhu, Ren, Linghuan, Tang, Yufei, Li, Xiaolong, Jian, Fan, Wang, Yan, Long, Hu, Lai, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034138/
https://www.ncbi.nlm.nih.gov/pubmed/33836649
http://dx.doi.org/10.1186/s12868-021-00632-5