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MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis

OBJECTIVES: Mounting evidence has demonstrated that microRNAs (miRNAs) participate in rheumatoid arthritis (RA). The role of highly conserved miR-15/107 family in RA has not been clarified yet, and hence investigated in this study. METHODS: Reverse transcription-quantitative polymerase chain reactio...

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Detalles Bibliográficos
Autores principales: Wang, Si, Xu, Jing, Guo, Yuanxu, Cai, Yongsong, Ren, Xiaoyu, Zhu, Wenhua, Geng, Manman, Meng, Liesu, Jiang, Congshan, Lu, Shemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034293/
https://www.ncbi.nlm.nih.gov/pubmed/33841401
http://dx.doi.org/10.3389/fimmu.2021.619392