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Blood leukocytes recapitulate diabetogenic peptide–MHC-II complexes displayed in the pancreatic islets

Assessing the self-peptides presented by susceptible major histocompatibility complex (MHC) molecules is crucial for evaluating the pathogenesis and therapeutics of tissue-specific autoimmune diseases. However, direct examination of such MHC-bound peptides displayed in the target organ remains large...

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Detalles Bibliográficos
Autores principales: Vomund, Anthony N., Lichti, Cheryl F., Peterson, Orion J., Arbelaez, Ana Maria, Wan, Xiaoxiao, Unanue, Emil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034384/
https://www.ncbi.nlm.nih.gov/pubmed/33822842
http://dx.doi.org/10.1084/jem.20202530