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Blood leukocytes recapitulate diabetogenic peptide–MHC-II complexes displayed in the pancreatic islets
Assessing the self-peptides presented by susceptible major histocompatibility complex (MHC) molecules is crucial for evaluating the pathogenesis and therapeutics of tissue-specific autoimmune diseases. However, direct examination of such MHC-bound peptides displayed in the target organ remains large...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034384/ https://www.ncbi.nlm.nih.gov/pubmed/33822842 http://dx.doi.org/10.1084/jem.20202530 |