Culture on a native bone marrow-derived extracellular matrix restores the pancreatic islet basement membrane, preserves islet function, and attenuates islet immunogenicity

Islet transplantation in man is limited by multiple factors including islet availability, islet cell damage caused by collagenase during isolation, maintenance of islet function between isolation and transplantation, and allograft rejection. In this study, we describe a new approach for preparing is...

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Detalles Bibliográficos
Autores principales: Wang, Hanzhou, Li, Shengxian, Dai, Qiuxia, Gonzalez, Aaron, Tran, Olivia N., Sun, Haiyan, DeFronzo, Ralph A., Dean, David D., Yeh, Chih-Ko, Chen, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034411/
https://www.ncbi.nlm.nih.gov/pubmed/32307751
http://dx.doi.org/10.1096/fj.201902893R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034411/
https://www.ncbi.nlm.nih.gov/pubmed/32307751
http://dx.doi.org/10.1096/fj.201902893R

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