Metformin attenuates post‐epidural fibrosis by inhibiting the TGF‐β1/Smad3 and HMGB1/TLR4 signaling pathways

Excessive post‐epidural fibrosis is a common cause of recurrent back pain after spinal surgery. Though various treatment methods have been conducted, the safe and effective drug for alleviating post‐epidural fibrosis remains largely unknown. Metformin, a medicine used in the treatment of type 2 diab...

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Detalles Bibliográficos
Autores principales: Song, Zeyuan, Wu, Tao, Sun, Jinpeng, Wang, Haoran, Hua, Feng, Nicolas, Yap San Min, KC, Rupesh, Chen, Kun, Jin, Zhen, Liu, Jun, Zhang, Mingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034438/
https://www.ncbi.nlm.nih.gov/pubmed/33611840
http://dx.doi.org/10.1111/jcmm.16398

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