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Nanoparticle formulation of mycophenolate mofetil achieves enhanced efficacy against hepatocellular carcinoma by targeting tumour‐associated fibroblast

Hepatocellular carcinoma (HCC) is one of the most aggressive tumours with marked fibrosis. Mycophenolate mofetil (MMF) was well‐established to have antitumour and anti‐fibrotic properties. To overcome the poor bioavailability of MMF, this study constructed two MMF nanosystems, MMF‐LA@DSPE‐PEG and MM...

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Detalles Bibliográficos
Autores principales: Yang, Zhentao, Zhang, Liang, Zhu, Hai, Zhou, Ke, Wang, Hangxiang, Wang, Yuchen, Su, Rong, Guo, Danjing, Zhou, Lin, Xu, Xiao, Song, Penghong, Zheng, Shusen, Xie, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034467/
https://www.ncbi.nlm.nih.gov/pubmed/33713546
http://dx.doi.org/10.1111/jcmm.16434