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Effects of Resmetirom on Noninvasive Endpoints in a 36‐Week Phase 2 Active Treatment Extension Study in Patients With NASH

Resmetirom (MGL‐3196), a selective thyroid hormone receptor‐β agonist, was evaluated in a 36‐week paired liver biopsy study (NCT02912260) in adults with biopsy‐confirmed nonalcoholic steatohepatitis (NASH). The primary endpoint was relative liver fat reduction as assessed by MRI–proton density fat f...

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Detalles Bibliográficos
Autores principales: Harrison, Stephen A., Bashir, Mustafa, Moussa, Sam E., McCarty, Kevin, Pablo Frias, Juan, Taub, Rebecca, Alkhouri, Naim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034581/
https://www.ncbi.nlm.nih.gov/pubmed/33860116
http://dx.doi.org/10.1002/hep4.1657