Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression

LuxR is a TetR family master quorum sensing (QS) regulator activating or repressing expression of hundreds of genes that control collective behaviors in Vibrios with underlying mechanism unknown. To illuminate how this regulator controls expression of various target genes, we applied ChIP-seq and DN...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Liu, Bing, Gu, Dan, Hao, Yuan, Chen, Mo, Ma, Yue, Zhou, Xiaohui, Reverter, David, Zhang, Yuanxing, Wang, Qiyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034623/
https://www.ncbi.nlm.nih.gov/pubmed/33693882
http://dx.doi.org/10.1093/nar/gkab150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034623/
https://www.ncbi.nlm.nih.gov/pubmed/33693882
http://dx.doi.org/10.1093/nar/gkab150

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