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TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei

The African trypanosome Trypanosoma brucei is a unicellular eukaryote, which relies on a protective variant surface glycoprotein (VSG) coat for survival in the mammalian host. A single trypanosome has >2000 VSG genes and pseudogenes of which only one is expressed from one of ∼15 telomeric bloodst...

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Detalles Bibliográficos
Autores principales: Davies, Carys, Ooi, Cher-Pheng, Sioutas, Georgios, Hall, Belinda S, Sidhu, Haneesh, Butter, Falk, Alsford, Sam, Wickstead, Bill, Rudenko, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034637/
https://www.ncbi.nlm.nih.gov/pubmed/33660774
http://dx.doi.org/10.1093/nar/gkab109