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TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei
The African trypanosome Trypanosoma brucei is a unicellular eukaryote, which relies on a protective variant surface glycoprotein (VSG) coat for survival in the mammalian host. A single trypanosome has >2000 VSG genes and pseudogenes of which only one is expressed from one of ∼15 telomeric bloodst...
Autores principales: | Davies, Carys, Ooi, Cher-Pheng, Sioutas, Georgios, Hall, Belinda S, Sidhu, Haneesh, Butter, Falk, Alsford, Sam, Wickstead, Bill, Rudenko, Gloria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034637/ https://www.ncbi.nlm.nih.gov/pubmed/33660774 http://dx.doi.org/10.1093/nar/gkab109 |
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