Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Protein methylation occurs primarily on lysine and arginine, but also on some other residues, such as histidine. METTL18 is the last uncharacterized member of a group of human methyltransferases (MTases) that mainly exert lysine methylation, and here we set out to elucidate its function. We found ME...

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Detalles Bibliográficos
Autores principales: Małecki, Jędrzej M, Odonohue, Marie-Francoise, Kim, Yeji, Jakobsson, Magnus E, Gessa, Luca, Pinto, Rita, Wu, Jie, Davydova, Erna, Moen, Anders, Olsen, Jesper V, Thiede, Bernd, Gleizes, Pierre-Emmanuel, Leidel, Sebastian A, Falnes, Pål Ø
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034639/
https://www.ncbi.nlm.nih.gov/pubmed/33693809
http://dx.doi.org/10.1093/nar/gkab088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034639/
https://www.ncbi.nlm.nih.gov/pubmed/33693809
http://dx.doi.org/10.1093/nar/gkab088

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