Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

DNA repair pathways are essential to maintain the integrity of the genome and prevent cell death and tumourigenesis. Here, we show that the Barrier-to-Autointegration Factor (Banf1) protein has a role in the repair of DNA double-strand breaks. Banf1 is characterized as a nuclear envelope protein and...

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Detalles Bibliográficos
Autores principales: Burgess, Joshua T, Cheong, Chee Man, Suraweera, Amila, Sobanski, Thais, Beard, Sam, Dave, Keyur, Rose, Maddison, Boucher, Didier, Croft, Laura V, Adams, Mark N, O’Byrne, Kenneth, Richard, Derek J, Bolderson, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034644/
https://www.ncbi.nlm.nih.gov/pubmed/33660778
http://dx.doi.org/10.1093/nar/gkab110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034644/
https://www.ncbi.nlm.nih.gov/pubmed/33660778
http://dx.doi.org/10.1093/nar/gkab110

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