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Validation of a human-serum-based in vitro growth method for drug screening on juvenile development stages of Schistosoma mansoni
BACKGROUND: Schistosomiasis affects over 200 million people worldwide but only praziquantel is available for treatment and control. Drug discovery is often based on phenotypic drug screening, involving different parasite stages retrieved from infected mice. Aiming to reduce animal use, we validated...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034724/ https://www.ncbi.nlm.nih.gov/pubmed/33784302 http://dx.doi.org/10.1371/journal.pntd.0009313 |