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Bromodomain-containing protein 4 silencing by microRNA-765 produces anti-ovarian cancer cell activity

Bromodomain-containing protein 4 (BRD4) overexpression promotes ovarian cancer progression, and represents an important therapeutic oncotarget. This current study identified microRNA-765 (miR-765) as a novel BRD4-targeting miRNA. We showed that miR-765 directly associated with and silenced BRD4. In...

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Detalles Bibliográficos
Autores principales: Ji, Yong-Jun, Shao, Yang, Zhang, Jie, Zhang, Xu, Qiang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034896/
https://www.ncbi.nlm.nih.gov/pubmed/33686960
http://dx.doi.org/10.18632/aging.202632