PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons

Caloric restriction has been shown to robustly ameliorate age-related diseases and to prolong lifespan in several model organisms, and these beneficial effects are dependent on the stimulation of autophagy. Autophagy dysfunction contributes to the accumulation of altered macromolecules, and is a key...

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Detalles Bibliográficos
Autores principales: Ferreira-Marques, Marisa, Carvalho, André, Cavadas, Cláudia, Aveleira, Célia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034898/
https://www.ncbi.nlm.nih.gov/pubmed/33714946
http://dx.doi.org/10.18632/aging.202805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034898/
https://www.ncbi.nlm.nih.gov/pubmed/33714946
http://dx.doi.org/10.18632/aging.202805

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