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Activation of ATF4 triggers trabecular meshwork cell dysfunction and apoptosis in POAG

Primary open angle glaucoma (POAG) is the leading cause of irreversible blindness. Dysfunction of the trabecular meshwork (TM), resulting in decreased outflow of aqueous humor and increased intraocular pressure (IOP), plays an important role in the pathogenesis of POAG. However, the underlying mecha...

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Detalles Bibliográficos
Autores principales: Ying, Ying, Xue, Ran, Yang, Yangfan, Zhang, Sarah X, Xiao, Hui, Zhu, Huazhang, Li, Jingming, Chen, Guo, Ye, Yiming, Yu, Minbin, Liu, Xing, Zhong, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034903/
https://www.ncbi.nlm.nih.gov/pubmed/33714955
http://dx.doi.org/10.18632/aging.202677