Cargando…
Activation of ATF4 triggers trabecular meshwork cell dysfunction and apoptosis in POAG
Primary open angle glaucoma (POAG) is the leading cause of irreversible blindness. Dysfunction of the trabecular meshwork (TM), resulting in decreased outflow of aqueous humor and increased intraocular pressure (IOP), plays an important role in the pathogenesis of POAG. However, the underlying mecha...
Autores principales: | Ying, Ying, Xue, Ran, Yang, Yangfan, Zhang, Sarah X, Xiao, Hui, Zhu, Huazhang, Li, Jingming, Chen, Guo, Ye, Yiming, Yu, Minbin, Liu, Xing, Zhong, Yimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034903/ https://www.ncbi.nlm.nih.gov/pubmed/33714955 http://dx.doi.org/10.18632/aging.202677 |
Ejemplares similares
-
AQP1 suppression by ATF4 triggers trabecular meshwork tissue remodelling in ET‐1‐induced POAG
por: Zhao, Yingying, et al.
Publicado: (2020) -
Upregulation of Copine1 in trabecular meshwork cells of POAG patients: a membrane proteomics approach
por: Zhang, Yuehong, et al.
Publicado: (2008) -
Inhibition of TGF-β2–Induced Trabecular Meshwork Fibrosis by Pirfenidone
por: Zhu, Xiaofeng, et al.
Publicado: (2023) -
Apoptosis in the trabecular meshwork of glaucomatous patients
por: Baleriola, Jimena, et al.
Publicado: (2008) -
Protein expression in human trabecular meshwork: downregulation of RhoGDI by dexamethasone in vitro
por: Yu, Minbin, et al.
Publicado: (2010)