Lifespan extension conferred by mitogen-activated protein kinase kinase kinase 5 (MAP3K5) longevity-associated gene variation is confined to at-risk men with a cardiometabolic disease

Genetic variants of the kinase signaling gene MAP3K5 are associated with longevity. Here we explore whether the longevity-association involves protection against mortality in all individuals, or only in individuals with aging-related diseases. We tested the strongest longevity associated single nucl...

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Detalles Bibliográficos
Autores principales: Morris, Brian J., Chen, Randi, Donlon, Timothy A., Masaki, Kamal H., Willcox, D. Craig, Allsopp, Richard C., Willcox, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034933/
https://www.ncbi.nlm.nih.gov/pubmed/33739303
http://dx.doi.org/10.18632/aging.202844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034933/
https://www.ncbi.nlm.nih.gov/pubmed/33739303
http://dx.doi.org/10.18632/aging.202844

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