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Inhibition of complement C5a receptor protects lung cells and tissues against lipopolysaccharide-induced injury via blocking pyroptosis

Acute lung injury (ALI) is the injury of alveolar epithelial cells and capillary endothelial cells caused by various factors. Complement system and pyroptosis have been proved to be involved in ALI, and inhibition of C5a/C5a receptor (C5aR) could alleviate ALI. This study aimed to investigate whethe...

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Detalles Bibliográficos
Autores principales: Wang, Renying, Wang, Yunxing, Hu, Lan, Lu, Zhenbing, Wang, Xiaoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034960/
https://www.ncbi.nlm.nih.gov/pubmed/33714207
http://dx.doi.org/10.18632/aging.202671