Transcriptome profiling reveals target in primary myelofibrosis together with structural biology study on novel natural inhibitors regarding JAK2

This study aimed to identify effective targets for carcinogenesis of primary myelofibrosis (PMF), as well as to screen ideal lead compounds with potential inhibition effect on Janus kinase 2 to contribute to the medication design and development. Gene expression profiles of GSE26049, GSE53482, GSE61...

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Detalles Bibliográficos
Autores principales: Li, Weihang, Yuan, Bin, Zhao, Yingjing, Lu, Tianxing, Zhang, Shilei, Ding, Ziyi, Wang, Dong, Zhong, Sheng, Gao, Guangxun, Yan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034969/
https://www.ncbi.nlm.nih.gov/pubmed/33686952
http://dx.doi.org/10.18632/aging.202635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034969/
https://www.ncbi.nlm.nih.gov/pubmed/33686952
http://dx.doi.org/10.18632/aging.202635

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