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Transcriptome profiling reveals target in primary myelofibrosis together with structural biology study on novel natural inhibitors regarding JAK2
This study aimed to identify effective targets for carcinogenesis of primary myelofibrosis (PMF), as well as to screen ideal lead compounds with potential inhibition effect on Janus kinase 2 to contribute to the medication design and development. Gene expression profiles of GSE26049, GSE53482, GSE61...
Autores principales: | Li, Weihang, Yuan, Bin, Zhao, Yingjing, Lu, Tianxing, Zhang, Shilei, Ding, Ziyi, Wang, Dong, Zhong, Sheng, Gao, Guangxun, Yan, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034969/ https://www.ncbi.nlm.nih.gov/pubmed/33686952 http://dx.doi.org/10.18632/aging.202635 |
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