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Silencing SIX1 by miR-7160 inhibits non-small cell lung cancer cell growth

The homeoprotein SIX1 is upregulated in non-small cell lung cancer (NSCLC) and associated with NSCLC tumorigenesis and progression. We identified microRNA-7160 (miR-7160) as a SIX1-targeting miRNA. RNA immunoprecipitation results confirmed a direct binding between miR-7160 and SIX1 mRNA in NSCLC cel...

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Detalles Bibliográficos
Autores principales: Zhao, Hua-Si, Tao, Xiao-Min, Wang, Qun, Fang, Yuan-Yuan, Zhang, Hong-Yu, Wang, Hua-Qi, Zhang, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034971/
https://www.ncbi.nlm.nih.gov/pubmed/33686961
http://dx.doi.org/10.18632/aging.202398