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Independence of chromatin conformation and gene regulation during Drosophila dorsoventral patterning

The relationship between chromatin organization and gene regulation remains unclear. While disruption of chromatin domains and domain boundaries can lead to misexpression of developmental genes, acute depletion of regulators of genome organization has a relatively small effect on gene expression. It...

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Detalles Bibliográficos
Autores principales: Ing-Simmons, Elizabeth, Vaid, Roshan, Bing, Xin Yang, Levine, Michael, Mannervik, Mattias, Vaquerizas, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035076/
https://www.ncbi.nlm.nih.gov/pubmed/33795866
http://dx.doi.org/10.1038/s41588-021-00799-x