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WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression

WW domain binding protein-2 (WBP2) can function as a Yes-associated protein/transcriptional co-activator with PDZ-binding motif (YAP/TAZ) co-activator and has a crucial role in promoting breast cancer progression. However, the expression and potential molecular mechanisms of WBP2 in the context of l...

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Detalles Bibliográficos
Autores principales: Han, Qiang, Rong, Xuezhu, Lin, Xuyong, Zhang, Xiupeng, Fan, Chuifeng, Zhao, Huanyu, Wang, Enhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035140/
https://www.ncbi.nlm.nih.gov/pubmed/33837178
http://dx.doi.org/10.1038/s41419-021-03600-3