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Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury

A major complication with spinal cord injury (SCI) is the development of spasticity, a clinical symptom of hyperexcitability within the spinal H-reflex pathway. We have previously demonstrated a common structural motif of dendritic spine dysgenesis associated with hyperexcitability disorders after i...

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Detalles Bibliográficos
Autores principales: Benson, Curtis A., Olson, Kai-Lan, Patwa, Siraj, Reimer, Marike L., Bangalore, Lakshmi, Hill, Myriam, Waxman, Stephen G., Tan, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035187/
https://www.ncbi.nlm.nih.gov/pubmed/33837249
http://dx.doi.org/10.1038/s41598-021-87476-5